Publications (past or present Rideout lab members shown in bold)
Millington JW, Brownrigg G, Basner-Collins PJ, Sun Z, Rideout EJ (2020). Genetic manipulation of insulin/insulin-like growth factor signaling pathway activity has sex-biased effects on Drosophila body size. bioRxiv.
Millington JW & Rideout EJ (2020). Stem cells on steroids: an important role for ecdysone in modulating sex differences in intestinal stem cell behaviour. Curr Bio. See bottom of the page for link to download the manuscript.
Millington JW, Chao C, Sun Z, Basner-Collins PJ, Brownrigg GP, Wat LW, Hudry B, Miguel-Aliaga I, Rideout EJ (2020). Female-specific upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity. bioRxiv. doi: 10.1101/2020.04.22.054239
Wat LW, Chao C, Bartlett R, Buchanan JL, Millington JW, Chih HJ, Chowdhury ZS, Biswas P, Huang V, Shin LJ, Wang LC, Gauthier MPL, Barone MC, Welte M, Montooth KL, Rideout EJ (2020). A role for triglyceride lipase brummer in the regulation of sex differences in Drosophila fat storage and breakdown. PLoS Biology. 18(1): e3000595. doi: 10.1371/journal.pbio.3000595.
Millington JW & Rideout, EJ (2018). Sex differences in Drosophila development and physiology. Curr. Opin. Physiol. 6: 46-56. See bottom of the page for link to download the manuscript.
Rideout EJ, Narsaiya MS, Grewal SS (2015). The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila body size. PLoS Genet. 11(12): e1005683. doi: 10.1371/journal.pgen.1005683.
Ghosh A, Rideout EJ, Grewal SS (2014). TIF-1A-dependent Regulation of Ribosome Synthesis in Drosophila Muscle is Required to Maintain Systemic Insulin Signaling and Larval Growth. PLoS Genet. 10(10): e1004750. doi: 10.1371/journal.pgen.1004750.
Marshall L, Rideout EJ, Grewal SS (2012). Nutrient/TOR-dependent regulation of RNA polymerase III controls tissue and organismal growth in Drosophila. EMBO J. 31(8): 1916-30. doi: 10.1038/emboj.2012.33.
Rideout EJ, Marshall L, Grewal SS (2012). Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling. Proc Natl Acad Sci USA. 109(4): 1139-44. doi: 10.1073/pnas.1113311109.
Rideout EJ, Dornan AJ, Neville MC, Eadie S, Goodwin SF (2010). Control of sexual differentiation and behavior by the doublesex gene in Drosophila melanogaster. Nat Neurosci. 13(4): 458-66. doi: 10.1038/nn.2515.
Aran V, Brandie FM, Boyd AR, Kantidakis T, Rideout EJ, Kelly SM, Gould GW, Bryant NJ (2009). Characterization of two distinct binding modes between syntaxin 4 and Munc18c. Biochem J. 419(3): 655-60. doi: 10.1042/BJ20082293.
Rideout EJ, Goodwin SF (2008). Sexual dimorphism: can you smell the difference? Curr Biol. 18(10):R425-7. doi: 10.1016/j.cub.2008.03.035.
Rideout EJ, Billeter JC, Goodwin SF (2007). The sex-determination genes fruitless and doublesex specify a neural substrate required for courtship song. Curr Biol. 17(17): 1473-8.
Billeter JC, Rideout EJ, Dornan AJ, Goodwin SF (2006). Control of male sexual behavior in Drosophila by the sex determination pathway. Curr Biol. 16(17): R766-76. Review.
Funding
Canadian Institutes of Health Research Sex and Gender Science Chair in Genetics (2020-2024).
Michael Smith Foundation for Health Research Scholar Award (2017-2022). Identifying the molecular mechanisms underlying sex differences in fat storage using Drosophila as a model.
Canadian Institutes of Health Research (2017-2022). Identifying genes and regulatory pathways that control sex differences in lipid storage using Drosophila as a model.
Natural Sciences and Engineering Research Council (2016-2022). Control of male-female differences in stress responses and survival by sex determination gene transformer.
Canadian Foundation for Innovation & British Columbia Knowledge Development Fund (2016). Facility for High-throughput Discovery of Sex Differences in Cellular Metabolism.
Undergraduate Student Funding
Yihan Xia (2020) Natural Sciences and Engineering Research Council (NSERC) Undergraduate Student Research Award
Kitty Sun (2019) Natural Sciences and Engineering Research Council (NSERC) Undergraduate Student Research Award
Yihan Xia (2019) UBC Faculty of Medicine Summer Student Research Program
Tiffany Chih (2017) Natural Sciences and Engineering Research Council (NSERC) Undergraduate Student Research Award
Vivian Huang (2017) UBC Faculty of Medicine Summer Student Research Program
Nazde Edeer (2016) UBC Faculty of Medicine Summer Student Research Program
Marcus Narsaiya (2016) ThermoFisher Summer Research Scholarship
Millington JW, Brownrigg G, Basner-Collins PJ, Sun Z, Rideout EJ (2020). Genetic manipulation of insulin/insulin-like growth factor signaling pathway activity has sex-biased effects on Drosophila body size. bioRxiv.
Millington JW & Rideout EJ (2020). Stem cells on steroids: an important role for ecdysone in modulating sex differences in intestinal stem cell behaviour. Curr Bio. See bottom of the page for link to download the manuscript.
Millington JW, Chao C, Sun Z, Basner-Collins PJ, Brownrigg GP, Wat LW, Hudry B, Miguel-Aliaga I, Rideout EJ (2020). Female-specific upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity. bioRxiv. doi: 10.1101/2020.04.22.054239
Wat LW, Chao C, Bartlett R, Buchanan JL, Millington JW, Chih HJ, Chowdhury ZS, Biswas P, Huang V, Shin LJ, Wang LC, Gauthier MPL, Barone MC, Welte M, Montooth KL, Rideout EJ (2020). A role for triglyceride lipase brummer in the regulation of sex differences in Drosophila fat storage and breakdown. PLoS Biology. 18(1): e3000595. doi: 10.1371/journal.pbio.3000595.
Millington JW & Rideout, EJ (2018). Sex differences in Drosophila development and physiology. Curr. Opin. Physiol. 6: 46-56. See bottom of the page for link to download the manuscript.
Rideout EJ, Narsaiya MS, Grewal SS (2015). The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila body size. PLoS Genet. 11(12): e1005683. doi: 10.1371/journal.pgen.1005683.
Ghosh A, Rideout EJ, Grewal SS (2014). TIF-1A-dependent Regulation of Ribosome Synthesis in Drosophila Muscle is Required to Maintain Systemic Insulin Signaling and Larval Growth. PLoS Genet. 10(10): e1004750. doi: 10.1371/journal.pgen.1004750.
Marshall L, Rideout EJ, Grewal SS (2012). Nutrient/TOR-dependent regulation of RNA polymerase III controls tissue and organismal growth in Drosophila. EMBO J. 31(8): 1916-30. doi: 10.1038/emboj.2012.33.
Rideout EJ, Marshall L, Grewal SS (2012). Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling. Proc Natl Acad Sci USA. 109(4): 1139-44. doi: 10.1073/pnas.1113311109.
Rideout EJ, Dornan AJ, Neville MC, Eadie S, Goodwin SF (2010). Control of sexual differentiation and behavior by the doublesex gene in Drosophila melanogaster. Nat Neurosci. 13(4): 458-66. doi: 10.1038/nn.2515.
Aran V, Brandie FM, Boyd AR, Kantidakis T, Rideout EJ, Kelly SM, Gould GW, Bryant NJ (2009). Characterization of two distinct binding modes between syntaxin 4 and Munc18c. Biochem J. 419(3): 655-60. doi: 10.1042/BJ20082293.
Rideout EJ, Goodwin SF (2008). Sexual dimorphism: can you smell the difference? Curr Biol. 18(10):R425-7. doi: 10.1016/j.cub.2008.03.035.
Rideout EJ, Billeter JC, Goodwin SF (2007). The sex-determination genes fruitless and doublesex specify a neural substrate required for courtship song. Curr Biol. 17(17): 1473-8.
Billeter JC, Rideout EJ, Dornan AJ, Goodwin SF (2006). Control of male sexual behavior in Drosophila by the sex determination pathway. Curr Biol. 16(17): R766-76. Review.
Funding
Canadian Institutes of Health Research Sex and Gender Science Chair in Genetics (2020-2024).
Michael Smith Foundation for Health Research Scholar Award (2017-2022). Identifying the molecular mechanisms underlying sex differences in fat storage using Drosophila as a model.
Canadian Institutes of Health Research (2017-2022). Identifying genes and regulatory pathways that control sex differences in lipid storage using Drosophila as a model.
Natural Sciences and Engineering Research Council (2016-2022). Control of male-female differences in stress responses and survival by sex determination gene transformer.
Canadian Foundation for Innovation & British Columbia Knowledge Development Fund (2016). Facility for High-throughput Discovery of Sex Differences in Cellular Metabolism.
Undergraduate Student Funding
Yihan Xia (2020) Natural Sciences and Engineering Research Council (NSERC) Undergraduate Student Research Award
Kitty Sun (2019) Natural Sciences and Engineering Research Council (NSERC) Undergraduate Student Research Award
Yihan Xia (2019) UBC Faculty of Medicine Summer Student Research Program
Tiffany Chih (2017) Natural Sciences and Engineering Research Council (NSERC) Undergraduate Student Research Award
Vivian Huang (2017) UBC Faculty of Medicine Summer Student Research Program
Nazde Edeer (2016) UBC Faculty of Medicine Summer Student Research Program
Marcus Narsaiya (2016) ThermoFisher Summer Research Scholarship
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